1260 Infinity II Analytical-Scale LC Purification System

The 1260 Infinity II Analytical-Scale LC Purification System is the most flexible and versatile solution for compound isolation within the InfinityLab LC purification portfolio. Ideal for purification of multi-milligram quantities of materials, the standard configuration handles flow rates between 0.1 and 10 mL/min with 2.1 and 10.0 mm id columns.

Easy-to-install upgrades are available for higher flow rates or lower dispersion. To meet diverse purification needs, UV or MS detection is possible as well as clustering of multiple fraction collectors



  • Analytical-scale purification LC system ideal for purification of multi-milligram quantities of materials
  • Highly reliable and robust LC system improve your ability to manage ever-increasing workload demand
  • Dynamic flow range up to 10 mL/min at maximum 600 bar allows versatile application within a wide range of analytical-scale purification workflows
  • Future-proof investment through upgrade with additional modules such as Infinity II refractive index, fluorescence, or evaporative light scattering detectors, or single quadrupole LC/MSD
  • Low-dispersion fraction collection for precise isolation of compounds of interest from your analytical run
  • Collection of up to 4 x 96 fractions in microtiter plates, or up to 216 fractions in glass tubes with 4 outer diameters of tubes available collector
  • Integrated and automated fraction delay sensor technology for increased purity and recovery of collected fractions
  • Upgradeable fraction capacity based on your demand: improved lab efficiency through orthogonal analytical information only available from isolated compounds
  • Fully upgradable to enhance the system’s capabilities and functionality based on your demand
  • Clean software infrastructure through Agilent OpenLab CDS ChemStation for familiar and reliable operation

How it works



Biocompatible No
Bioinert No
Column Capacity 4
Column ID Reader Option Optional
Depth 468 mm
Flow Range 0.05 to 5 mL/min with G7112B

0.2 to 10 mL/min with G7110B, G7111A, G7111B

Injection Range 0.1-100 µL

0.1-900 µL with Extended Injection Range Option

0.1 to 1800 µL with Multi Draw Kit

Intelligent System Emulation Technology No
Line Voltage 100-240 VAC
Maximum Number of Fractions 384
Maximum Number of Solvents 4 up to 15 with additional Solvent Selection Valve
Maximum Number of Temperature Zones 2 with G7116A/B

1 with Vial Sampler with Integrated Column Compartment

Pump Type Binary
Special Features Delay Sensor

Automated Delay Volume Calibration

System Pressure Operating Range up to 600 bar
Width 980mm