1260 Infinity II Prime LC System

The 1260 Infinity II Prime LC is a versatile HPLC offering the highest functionality and operational convenience for analytical HPLC and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min. This versatile HPLC system is a perfect front end for your MS system.

The 1260 Infinity II Prime LC has gradient and mixing performance equivalent to a 1260 binary system, provides quaternary and ternary solvent mixing, and offers functions like intelligent system emulation technology (ISET) for perfect method transfer. BlendAssist enables automatic mobile phase blending by using 1290 Infinity II Flexible Pump technology.

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Features

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    • Offers ultimate gradient and mixing performance equivalent to a 1260 binary system and provides quaternary and ternary solvent mixing. Combines the best of the two worlds of 1260 quaternary and 1260 binary systems with good accuracy and precision for flow rates up to 5 mL/min within a pressure range up to 800 bar
    • Seamless transfer of methods between LCs regardless of the brand, facilitated by proprietary Agilent Intelligent System Emulation Technology (ISET) as part of the pump, delivering unchanged retention time and peak resolution
    • Simplify your workflow: The pump driver-based feature BlendAssist delivers accurately buffer/additive blending without manual interaction
    • Reduce the need for manual interaction: With the Multipurpose valve built into the 1260 Infinity II Flexible Pump, you can purge your instrument via software
    • Ultralow carryover: The multiwash capability of the new 800 bar-rated 1260 Infinity II Multisampler cleans all relevant injection parts between runs. This sophisticated, integrated feature flushes the injection needle outside with three solvents, and uses seat backflush procedures to reduce carryover to less than 10 ppm
    • Efficient sample handling and logistics: Using shallow microplate drawers, the 1260 Infinity II Multisampler takes a maximum load of 16 microtiter plates and up to 6,144 samples - the most of any single system
    • Efficient column handling and temperature control: The 1260 Infinity II Multicolumn Thermostat holds up to four columns with direct access to each column through a InfinityLab Quick Change switching valve, eliminating the need to disconnect and reconnect columns
    • Improved flexibility: Set up your LC system to suit the way you work, with the InfinityLab Benchtop shelving system
    • Stay at your desk: With the new InfinityLab LC Companion local user interface, you can access and control your instrument comfortably from your office or other locations
    • Perfect front-end for everyday MS analysis: Performing like a high-pressure mixing system and offering convenient features to get to the optimum results faster
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Biocompatible
  • No
Bioinert
  • No
Column Capacity
  • 4
Column ID Reader Option
  • Optional
Depth
  • 468 mm
Flow Range
  • up to 5 mL/min with G7104C
Injection Range
  • 0.1-100 µL
  • 0.1 to 1500 µL with Multi Draw Kit
Intelligent System Emulation Technology
  • Optional
Line Voltage
  • 100-240 VAC
Maximum Number of Solvents
  • 4
  • up to 26 with additional Solvent Selection Valve
Maximum Number of Temperature Zones
  • 2 with G7116A/B
  • 1 with Vial Sampler with Integrated Column Compartment
Pump Type
  • Flexible
Special Features
  • Blend Assist
System Pressure Operating Range
  • up to 800 bar
Width
  • 435 mm
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Seamless Method Transfer from a Waters Alliance LC to an Agilent 1260 Infinity II Prime LC using ISET

A demonstration of the straightforward analytical method transfer from the Waters Alliance 2695 LC to an Agilent 1260 Infinity II Prime LC by using ISET.

Agilent 1260 Infinity II Flexible Pump with Blend Assist

The Agilent 1260 Infinity II Flexible Pump with Blend Assist allows a straightforward variation of modifier/buffer concentration and so circumvents the need for manual mixing of different concentrations

Improving Return on Investment in Liquid Chromatography with the InfinityLab LC Series

This interactive white paper illustrates the incremental economic value of the Agilent 1260 Infinity II Prime LC compared to a conventional LC system.

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Hyoscine Butylbromide Analysis by British Pharmacopoeia Method-1260InfinityIIPrimeLC

Analysis of Hyoscine Butylbromide by Agilent 1260 Infinity II Prime LC According to the New British Pharmacopoeia

Meeting California Cannabis Regulations with the Agilent 1260 Infinity II Prime LC and Agilent Ultivo Triple Quadruple MS

A method from Weck Labs for assessing pesticides, mycotoxins, and potency in cannabis flowers.

Veterinary Drug Detection in Pork and Milk

A 10 minute analytical method for the precise quantification of 12 regulated veterinary drug compounds in pork and milk.

Analysis of Doxorubicin Hydrochloride with the New Agilent 1260 Infinity II Prime LC as per USP Monograph Method

Describes the analysis of doxorubicin hydrochloride according to an updated USP method with the Agilent 1260 Infinity II Prime LC.

Analysis of Antihistaminic Drugs using the Agilent 1260 Infinity II Prime LC

Agilent 1260 Infinity II Prime LC with ISET – emulation of the Agilent 1200 Series Quaternary LC for analysis of antihistaminic drugs.

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Agilent InfinityLab LC Series - Efficient LC solutions for any application and budget

From routine analysis to cutting-edge research, the Agilent InfinityLab LC Series offers the broadest portfolio of HPLC solutions.

Agilent 1260 Infinity II Prime LC: Achieve convenience - every day in every way

The Agilent 1260 Infinity II Prime LC is the most capable and convenient LC within the 1260 Infinity II LC portfolio.

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Version Europe - Now Is the Perfect Time to Refresh Your LC Technology

Make a smooth transition with the Agilent 1200 Series LC refresh program

Hong Kong Version - Now Is the Perfect Time to Refresh Your LC Technology

Make a smooth transition with the Agilent 1200 Series LC refresh program

Now Is the Perfect Time to Refresh Your LC Technology

Make a smooth transition with the Agilent 1200 Series LC refresh program

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LC Troubleshooting Guide

This poster will become the most helpful quick reference tool in your lab. It includes detailed information on how to overcome the most common troubleshooting issues.

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Let Your Autosampler Do Your Pipetting

Describes how the injector program with the Agilent 1260 Infinity II Prime LC System with 1260 Infinity II Vialsampler or 1260 Infinity II Multisampler can prepare calibration solutions.

The Agilent 1260 Infinity II Flexible Pump the Benchmark for Accuracy and Precision

The Agilent 1260 Infinity II Flexible Pump demonstrates excellent performance for retention time precision in various challenging LC applications where a binary pump is normally advantageous.

Comparison of the 800 bar and 600 bar Agilent 1260 Infinity II Vialsampler

Comparison of the reproducibility, resolution, linearity, and sensitivity of the 800 and 600 bar 1260 Infinity II Vialsamplers by the analysis of corticosteroids

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Improving Return on Investment with Smart, Integrated InfinityLab Solutions

Whitepaper demonstrating the incremental economic value of the Agilent 1260 Infinity II Prime LC and the InfinityLab LC/MSD iQ, including interactive ROI calculators.

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Agilent InfinityLab Supplies for the Agilent 1260 Infinity II Prime System

A list of the most commonly ordered supplies and parts for the 1260 Infinity II Prime System.

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Vialsamplers Agilent InfinityLab LC Series User Manual

This manual contains technical reference information about the Agilent 1260 Infinity II Vialsampler (G7129A), Agilent 1260 Infinity II Vialsampler (G7129C) and the Agilent 1290 Infinity II Vialsampler (G7129B).

Diode Array Detector WR and Multiple Wavelength Detector Agilent InfinityLab LC Series User Manual

This manual contains technical information about the Agilent 1260 Infinity II Diode Array and Multiple Wavelength Detectors G7115A WR and G7165A.

InfinityLab LC Series Multisamplers User Manual

Technical information about the Agilent 1290 Infinity II Multisampler (G7167B), 1260 Infinity II Multisampler (G7167A) and 1260 Infinity II Bio-inert Multisampler (G5668A).

InfinityLab LC Series Variable Wavelength Detectors User Manual

Technical information about the 1290 Infinity II Variable Wavelength Detector (G7114B) and the 1260 Infinity II Variable Wavelength Detector (G7114A).

InfinityLab LC Series 1260 Infinity II Flexible Pump User Manual

This manual covers the Agilent 1260 Infinity II Flexible Pump (G7104C).

Best Practices for Addressing Problems Associated With Unstable Solvents in an (U)HPLC Environment

This technote provides an overview on how to operate safely with unstable solvents in an (U)HPLC environment and how to avoid damage to the instrument or separation column.

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LC Application Finder

Search for LC Application Notes and Technical Overviews
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Specifications

Video

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