1290 Infinity II Preparative LC/MSD System

The 1290 Infinity II Preparative LC/MSD System enables high-throughput purification, delivering high-quality compounds, for example, for biological screening, an important part of drug discovery.

This system features the Agilent 1290 Infinity II Preparative Open-Bed Sampler/Collector and offers outstanding flexibility in terms of application area and bench space. Mass-selective fraction triggering streamlines your purification processes and helps boost laboratory efficiency by reducing your reanalysis time.

Product details Related Product


  • Preparative LC/MSD System with fully automated combined sample injection fraction collection to maximize your capacity to increase your daily throughput, maximize purity, and minimize reanalysis time by mass-based purifcation
  • Focusing solely on your target compounds to minimize reanalysis time and reformulation of collected fractions
  • Highly reliable and robust LC system improves your ability to manage ever-increasing workload demand
  • Easy-to-change pump heads provide dynamic flow range up to 200 mL/min at maximum 600 bar for versatile application within a wide range of preparative workflows
  • Control and organization of valves: five multipurpose slots provide enhanced organization of valves, fraction delay coils, and Agilent 1290 Infinity II MS Flow Modulator for a significant increase in productivity
  • Integration of all standard collection modes and compatibility with multiple trigger sources provides compatibility to existing purification methods
  • Lowest delay volume to minimize peak dispersion and carry-over for the highest sample recovery and purity
  • Clean software infrastructure through Agilent OpenLab CDS ChemStation for familiar and reliable operation


Biocompatible No
Bioinert No
Column Capacity 10
Column ID Reader Option No
Depth 622 mm
Flow Range 1-200 mL/min
Injection Range 5-15700 µL
Intelligent System Emulation Technology No
Line Voltage 100-240 VAC
Maximum Number of Fractions 432
Maximum Number of Solvents 4
Pump Type Binary
Special Features Delay Sensor

Automated Delay Volume Calibration

System Pressure Operating Range 20-600 bar
Width 1585 mm



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