1290 Infinity II LC System

The 1290 Infinity II LC System is an ultra-high performance LC that has market-leading sample capacity and is designed for the lowest dispersion for the most challenging ultra-HPLC experiments. The 1290 Infinity II LC system is designed to be both a HPLC and high-end UHPLC system in a single flow path, giving you robust and excellent performance no matter what application you are running while seamlessly integrating into your existing laboratory environment.

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  • More chromatographic resolution from specially designed components in the sample flow path to achieve the lowest system dispersion
  • Higher peak capacity for challenging separations - switch easily between single dimension high-end UHPLC and the ultimate chromatographic power of 2D-LC
  • Lower carryover for uncompromised data quality - multiwash capabilities of the Agilent 1290 Infinity II Multisampler reduce carryover to less than 10 ppm even for challenging compounds such as chlorohexidine
  • Unique detection capabilities - combine lowest detection limits with an ultrawide dynamic range by using the new Agilent 1290 Infinity II HDR-DAD or 1290 Infinity II ELSD
  • Faster injection cycles with dual-needle injection - for higher sample throughput
  • Higher sample capacity per bench space - up to 6144 samples within the footprint of a standard Agilent stack
  • Flexibility for all applications - through wide power, temperature, an automatically scalable injection range, and gradient options
  • Seamless transfer of methods between LCs, regardless of the brand - facilitated by intelligent system emulation technology (ISET) delivering unchanged retention time and peak resolution
  • Seamless integration in your chromatography data system - Agilent InfinityLab LC instrumentation runs smoother when controlled through third-party chromatography data systems such as Waters Empower or Thermo Scientific’s Chromeleon using the Agilent instrument control framework (ICF)
  • Lower total cost of ownership - select from a variety of tools to achieve lowest cost-per-sample


Column Capacity
  • 8
Column ID Reader Option
  • Optional
  • 468 mm
Flow Range
  • up to 5 mL/min with G7120A and G7104A
Injection Range
  • 0.1-100 µL
  • 0.1 to 1500 µL with Multi Draw Kit
Intelligent System Emulation Technology
  • Optional
Line Voltage
  • 100-240 VAC
Maximum Number of Solvents
  • 4
  • up to 15 with additional Solvent Selection Valve
Maximum Number of Temperature Zones
  • 2 with G7116B
  • 1 with Vial Sampler with Integrated Column Compartment
Pump Type
  • Binary
  • Flexible
Special Features
  • Blend Assist with G7104A
System Pressure Operating Range
  • up to 1300 bar
  • 435 mm



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