1290 Infinity II LC System

1290 Infinity II LC System

The 1290 Infinity II LC System is an ultra-high performance LC that has market-leading sample capacity and is designed for the lowest dispersion for the most challenging ultra-HPLC experiments. The 1290 Infinity II LC system is designed to be both a HPLC and high-end UHPLC system in a single flow path, giving you robust and excellent performance no matter what application you are running while seamlessly integrating into your existing laboratory environment.


Features

    • More chromatographic resolution from specially designed components in the sample flow path to achieve the lowest system dispersion
    • Higher peak capacity for challenging separations – switch easily between single dimension high-end UHPLC and the ultimate chromatographic power of 2D-LC
    • Lower carryover for uncompromised data quality – multiwash capabilities of the Agilent 1290 Infinity II Multisampler reduce carryover to less than 10 ppm even for challenging compounds such as chlorohexidine
    • Unique detection capabilities – combine lowest detection limits with an ultrawide dynamic range by using the new Agilent 1290 Infinity II HDR-DAD or 1290 Infinity II ELSD
    • Faster injection cycles with dual-needle injection – for higher sample throughput
    • Higher sample capacity per bench space – up to 6144 samples within the footprint of a standard Agilent stack
    • Flexibility for all applications – through wide power, temperature, an automatically scalable injection range, and gradient options
    • Seamless transfer of methods between LCs, regardless of the brand – facilitated by intelligent system emulation technology (ISET) delivering unchanged retention time and peak resolution
    • Seamless integration in your chromatography data system – Agilent InfinityLab LC instrumentation runs smoother when controlled through third-party chromatography data systems such as Waters Empower or Thermo Scientific’s Chromeleon using the Agilent instrument control framework (ICF)
    • Lower total cost of ownership – select from a variety of tools to achieve lowest cost-per-sample

Specifications

Column Capacity
  • 8
Column ID Reader Option
  • Optional
Depth
  • 468 mm
Flow Range
  • up to 5 mL/min with G7120A and G7104A
Injection Range
  • 0.1-100 µL
  • 0.1 to 1500 µL with Multi Draw Kit
Intelligent System Emulation Technology
  • Optional
Line Voltage
  • 100-240 VAC
Maximum Number of Solvents
  • 4
  • up to 15 with additional Solvent Selection Valve
Maximum Number of Temperature Zones
  • 2 with G7116B
  • 1 with Vial Sampler with Integrated Column Compartment
Pump Type
  • Binary
  • Flexible
Special Features
  • Blend Assist with G7104A
System Pressure Operating Range
  • up to 1300 bar
Width
  • 435 mm

Literature

LC Troubleshooting Guide

This poster will become the most helpful quick reference tool in your lab. It includes detailed information on how to overcome the most common troubleshooting issues.

Optimizing System Dispersion on the Agilent 1290 Infinity II LC

The 1290 Infinity II LC equipped with ultralow dispersion kit achieves significantly lower band-broadening than comparable UHPLC system from another vendor.

Hyoscine Butylbromide Analysis by British Pharmacopoeia Method-1260InfinityIIPrimeLC

Analysis of Hyoscine Butylbromide by Agilent 1260 Infinity II Prime LC According to the New British Pharmacopoeia

Meeting California Cannabis Regulations with the Agilent 1260 Infinity II Prime LC and Agilent Ultivo Triple Quadruple MS

A method from Weck Labs for assessing pesticides, mycotoxins, and potency in cannabis flowers.

Veterinary Drug Detection in Pork and Milk

A 10 minute analytical method for the precise quantification of 12 regulated veterinary drug compounds in pork and milk.

Analysis of Doxorubicin Hydrochloride with the New Agilent 1260 Infinity II Prime LC as per USP Monograph Method

Describes the analysis of doxorubicin hydrochloride according to an updated USP method with the Agilent 1260 Infinity II Prime LC.

Analysis of Antihistaminic Drugs using the Agilent 1260 Infinity II Prime LC

Agilent 1260 Infinity II Prime LC with ISET – emulation of the Agilent 1200 Series Quaternary LC for analysis of antihistaminic drugs.

The Analytical Scientist: Exploring the Economics of Innovation

The Analytical Scientist: Exploring the Economics of Innovation

The Guide to Improved Efficiency

Improve efficiency in your liquid chromatography workflow. Learn from your peers and get tips and tricks from the experts in this e-book from the Analytical Scientist.

The LC Side of “Do More with Less”

This eBook features unique Agilent InfinityLab LC Solutions developed to solve the everyday, but certainly not “routine”, problems in the modern laboratory.

Enhance Your Proteomics Research

Proteomics Solutions For Your Application

Agilent InfinityLab LC Solutions

Reliable, efficient, always innovating for your best result. Learn more about our comprehensive portfolio of Agilent InfinityLab LC Solutions.

The Agilent 6546 LC/Q-TOF Accelerate Capablilities

The 6546 LC/Q-TOF enables you to simultaneously obtain high speed, high resolution, and wide dynamic range.

Guide to Peptide Quantitation

Agilent is ideally qualified and happy to be the company that can assist you in your peptide quantitation journey.

Proven Solutions for Clinical Research

Agilent analytical research method guide

Agilent 1290 Infinity II LC: Set new benchmarks in efficiency with the next generation of UHPLC

The Agilent 1290 Infinity II LC embodies the next generation of UHPLC .

Agilent CE and CE/MS Solutions – Flexibility and Reliability to Amplify your Findings

AThis brochure details how Agilent provides a complete and truly integrated single-vendor solution for combined CE and CE/MS analysis.

TOF and Q-TOF LC/MS Forensic Toxicology PCDL and Application Kit flyer

Simplify your startup for untargeted drug screening. Screen samples quickly and easily using the Forensic Toxicology Accurate Mass Database and Library. For forensic use.

Agilent InfinityLab LC Series Instruments Are Now Within Your Reach.

Lower pricing is just the beginning. Need efficient LC technology that keeps repair costs and downtime to a minimum? Want to be part of a group of chemists who benefit from insights that optimize lab operations? There’s never been a better time to choose Agilent.

Version Europe – Now Is the Perfect Time to Refresh Your LC Technology

Make a smooth transition with the Agilent 1200 Series LC refresh program

Hong Kong Version – Now Is the Perfect Time to Refresh Your LC Technology

Make a smooth transition with the Agilent 1200 Series LC refresh program

Now Is the Perfect Time to Refresh Your LC Technology

Make a smooth transition with the Agilent 1200 Series LC refresh program

Forensic Toxicology tMRM Database

Streamline targeted screening of forensic toxicology compounds with database of MRM transitions. Minimize the need for tedious method development. Learn more.

Forensic Toxicology LC/MS Personal Compound Database and Library

Simplify your comprehensive screening of forensic toxicology compounds. Confidently perform target and suspect screening using accurate mass. Screen for more than 9,000 analyt

A Fast LC/MS/MS Method for the Simultaneous Analysis of Barbiturates

The main goal of this work was to combine Barbiturates and THC-A into a single method.

Enhanced Lipids Removal From Biological Matrices to Prepare Samples

Lipids, especially phospholipids (PPLs), in biological matrices can significantly impact bioanalysis quality by LC/MS/MS.

Enhanced Analysis of Host Cell Proteins from CHO cell cultured mAb using LC/MS

ASMS Poster 2017 – WP694 (4 Page Layout)

Quantifying metals in solvents via ICP-MS/MS & separating metal complexes by GPC with a LC-ICP-MS/MS

An ICP-MS/MS tailored for organics measured <100 ppt elements in organic solvents. LC-ICP-MS/MS coupling was feasible for size speciation of metals in petrochemicals.>

Efficient LC method development

The poster provides useful information about particle sizes, column chemistry and protocol setup.

Ultrafast Analysis of Food Preservatives Using Automated Column Regeneration and Dual-Needle Injection

HPLC 2015 official scientific poster

G4239C 8Pos/18Port, 1300bar Valve

G4239C 8Pos/18Port, 1300bar Valve

InfinityLab LC/MSD iQ: An intuitive and self-aware mass detector for unambiguous mass confirmation to enhance chromatographic results

InfinityLab LC/MSD iQ: An intuitive and self-aware mass detector for unambiguous mass confirmation to enhance chromatographic results

Robustness of the Agilent Ultivo LC/TQ for High-Throughput Testing of Drugs in Serum

Robustness study of Agilent Ultivo LC/TQ with ESI source for detection of 26 drugs in human serum.

Automated LC Method Development and Robustness Tests

Showcases the use of the Agilent Instrument Control Framework to develop 2D-LC methods with the Agilent Infinity II LC and ChromSwordAuto 5.

Auto MS/MS and Identification of Unknowns in Water Samples

In this Technical Overview, we carefully explain and optimize all the parameters included in the data dependent acquisition mode of Agilent quadrupole time-of-flight instruments, Auto MS/MS.

Comparison of Reversed-Phase Column Types for Peptide Mapping Separations

Evaluation of the commercially available reversed-phase peptide column types for LC/MS


Support

1290 Infinity II LC System Ordering Details

Ordering information for the 1290 Infinity II LC System

InfinityLab LC Series Installation Checklist

This checklist Rev. B.00 is used by the installing engineer to ensure that the instrument and associated systems are correctly installed.

Agilent InfinityLab Supplies for the Agilent 1290 Infinity II LC with Multisampler

A list of the most commonly ordered supplies and parts for the 1290 Infinity II LC with Multisampler.

InfinityLab LC Series Site Preparation Checklist

InfinityLab LC Series Site Preparation Checklist

Vialsamplers Agilent InfinityLab LC Series User Manual

This manual contains technical reference information about the Agilent 1260 Infinity II Vialsampler (G7129A), Agilent 1260 Infinity II Vialsampler (G7129C) and the Agilent 1290 Infinity II Vialsampler (G7129B).

InfinityLab LC Series Multisamplers User Manual

Technical information about the Agilent 1290 Infinity II Multisampler (G7167B), 1260 Infinity II Multisampler (G7167A) and 1260 Infinity II Bio-inert Multisampler (G5668A).

InfinityLab LC Series Refractive Index Detector User Manual

This manual contains information about the Agilent 1260 Infinity II Refractive Index Detector (G7162A) and the Agilent 1290 Infinity II Refractive Index Detector (Micro G7162B

InfinityLab LC Series 1290 Infinity II High Speed Pump User Manual

This manual contains technical reference information about the Agilent 1290 Infinity II High Speed Pump G7120A.

InfinityLab LC Series Variable Wavelength Detectors User Manual

Technical information about the 1290 Infinity II Variable Wavelength Detector (G7114B) and the 1260 Infinity II Variable Wavelength Detector (G7114A).

InfinityLab LC Series Diode Array Detectors User Manual

Technical information about the Agilent 1290 Infinity II Diode Array Detector FS (G7117A), Diode Array (G7117B), and 1260 Infinity II Diode Array Detector HS (G7117C).

1290 Infinity II LC System Manual and Quick Reference

This manual contains technical reference information about the Agilent 1290 Infinity II LC.

InfinityLab LC Series 1290 Infinity II Flexible Pump User Manual

This manual contains technical reference information about the Agilent 1290 Infinity II Flexible Pump G7104A.

Best Practices for Addressing Problems Associated With Unstable Solvents in an (U)HPLC Environment

This technote provides an overview on how to operate safely with unstable solvents in an (U)HPLC environment and how to avoid damage to the instrument or separation column.


Tools

LC Application Finder

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