Food Testing Agriculture

Why LC/MS/MS and GC/MS/MS Are Required for the Analysis of Certain Pesticides

Residual pesticide analysis in cannabis matrices is arguably the most challenging of all the mandated regulatory assays due to the complexity of the matrix and the very low action limits. Further complicating the issue is the inclusion of pesticides not amenable to electrospray ionization (ESI), the most common LC/MS/MS ionization source for this analysis. For example, California and Canada have included pentachloronitrobenzene (PCNB) in their target list.