This Application Note demonstrates the use of the Agilent J&W DB-HeavyWAX GC column for the analysis of e-cigarette liquid using an Agilent 7890 and Agilent Intuvo 9000 gas chromatograph. E-cigarette liquids can contain many fruit flavor compounds that require a higher final temperature or longer run time to elute off the column. The DB-HeavyWAX has a maximum isothermal temperature of 280 °C and programmed temperature of 290 °C, with increased thermal stability, allowing for the efficient analysis of later eluting and higher boiling compounds